21c Museum Hotel Louisville

Located within Louisville’s exciting West Main Street Historic District is the 21c Museum Hotel Louisville: the flagship establishment of 21c Museum Hotels. It has many pieces of contemporary artwork, including a fantastic remake of Michelangelo’s David situated just beyond its front door. The current building is composed of five historical warehouses that once catered to the tobacco and bourbon merchants that frequented the city’s vibrant riverside port. One of the structures even served as the lucrative Falls City Tobacco Bank for several decades during the mid-1800s. Since 2006, these marvelous historical buildings have together formed the 21c Museum Hotel Louisville. The hotel features 91 guestrooms and contemporary art museum. 21c Museum Hotel Louisville has been named to these Historic Hotels of America Top 25 Lists The 2023 Top 25 Historic Hotels of America® Most Magnificent Art Collections The 2022 Top 25 Historic Hotels of America Most Magnificent Art Collections